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"Challenges in Parkinsons Disease" ed. by Jolanta Dorszewska and Wojciech Kozubski

"Challenges in Parkinsons Disease" ed. by Jolanta Dorszewska and Wojciech Kozubski
English | ITexLi | 2016 | ISBN: 9535124641 9535124633 | 400 pages | PDF | 56 MB
This book is a sum up of knowledge on the genetic factors and neuronal death mechanisms induced by excitotoxic and inflammatory agents. The authors summarize the pathophysiology observed both in patients with Parkinsons disease and in experimental models.

The book contains the latest views on drug therapy used in the treatment of parkinsonism and other therapeutic approaches for Parkinsons disease.

Parkinsons disease is a common neurological disease and affects 2% population of more than 65 years of age and 5% more than 85 years of age. Pathomechanism of this disease is still not fully understood.

Contents
Preface
1 Introductory Chapter - Genetic and Biochemical Factors in Parkinsons Disease
2 Genetics of Parkinsons Disease: The Role of Copy Number Variations
3 Mechanisms for Neuronal Cell Death in Parkinsons Disease: Pathological Cross Talks Between Epigenetics and Various Signalling Pathways
4 Inflammation: Role in Parkinsons Disease and Target for Therapy
5 Chronic Inflammation Connects the Development of Parkinsons Disease and Cancer
6 Is Chronic Systemic Inflammation a Determinant Factor in Developing Parkinsons Disease?
7 Disorders of Sleep and Motor Control During the Impaired Cholinergic Innervation in Rat - Relevance to Parkinsons Disease
8 Cognitive Impairment in Parkinsons Disease: Historical Review, Past, and Present
9 Brain Network Metabolic Changes in Patients with Parkinsonian Tremors
10 Animal Models of Parkinsons Disease
11 Understanding Pathophysiology of Sporadic Parkinsons Disease in Drosophila Model: Potential Opportunities and Notable Limitations
12 Pharmacotherapeutic Challenges in Parkinsons Disease Inpatients
13 Clinical and Experimental Cell Therapy in Parkinsons Disease
14 Cell-Based Therapies for Parkinsons Disease: Preclinical and Clinical Perspectives
15 Stem Cell Therapy for Parkinsons Disease
16 Surgical Therapy of Parkinsons Disease
17 Neuro-Ophthalmologic Evaluation as a Biomarker for Diagnosis and Progression in Parkinson Disease
18 Possible Treatments of Atypical Parkinsonism
19 The Role of Nurses in Parkinsons Disease

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Tags: Challenges, Parkinsons, Disease, Jolanta, Dorszewska, Wojciech, Kozubski

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