Jeffrey A. Frelinger, "Immunodominance: The Choice of the Immune System"
English | 2006 | ISBN: 3527312749 | 314 pages | PDF | 5 MB
This very first handbook on the topic summarizes the current concepts and brings together in one volume the critical arguments concerning the mechanisms relevant to immunodominance. In invited chapters written by the leaders in the field, the mechanisms whereby the immune system chooses the parts of a recognized pathogen in order to start the immune response are explained and the variety of biologic processes are identified that contribute to that choice.
From the contents:
Mechanics of antigen processing
Proteosome specificity and immuno-proteosomes
Effect of the T cell repertoire on dominance
Effects of pathogens on the immune response