Cancer Epigenetics: Methods and Protocols by Ramona G. Dumitrescu
English | 25 Feb. 2012 | ISBN: 1617796115, 1617796131 | 487 Pages | PDF | 6 MB
The epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation.
More recently, epigenetic changes have been observed in early stages of tumor development and together with the genetic alterations have been defined as abnormalities, necessary for cancer initiation and progression.
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